CBD is already known to have analgesic and anti-inflammatory effects, but research is still underway into further properties of the substance. It turns out that the cannabinoid CBD can also be effective in treating nausea.
CBD and nausea
Research on the effectiveness of effects of CBD in the fight against nausea are at an advanced stage, but have not yet been carried out on humans. Recent animal studies, however, show promising results. In mice treated with CBD, vomiting and nausea were noticeably reduced. Standard antiemetic drugs most often only relieve nausea, rather than eliminating it completely. Scientists believe that the following may be helpful in this case CBD combination and THC.
One study showed that Sativex (the drug Cannabinoid containing a combination of THC and CBD) taken in combination with other antiemetic therapies, has helped eliminate nausea and vomiting completely for some patients.
It is worth noting, however, that according to some researchers, it is crucial to choose the right dose of the substance when taking CBD. If too much is taken, the effect can be counterproductive, which, combined with other side effects, can lead to nausea.
The endocannabinoid system
The endocannabinoid system (ECS) has been noted to exist in all vertebrates and is responsible for regulating key vital functions such as sleep, appetite and pain. The human body is able to independently produce chemical compounds that modulate and activate its functions, but thanks to the endocannabinoid system, the same role can be fulfilled by cannabinoids found in the cannabis plant.
The ECS was discovered just 30 years ago, and scientists still have much to learn about the myriad ways in which the Cannabis can affect the performance of human receptors. It turns out that the endocannabinoid system is also responsible for the sensation of nausea.
How does CBD work for nausea?
We still don't have extensive knowledge on the subject, and there's still a lot of research ahead of us, but animal tests have provided some insight into the effects of CBD on the endocannabinoid system for nausea. Human subjects with nausea have been noted to have lower values of the endocannabinoids produced in the human body The endocannabinoids anandamide and 2-AG.
These patients also had fewer CB1 receptors, one of the main receptors in the endocannabinoid system. In contrast, inducing motion sickness with parabolic flight maneuvers led to an early increase in anandamide and a subsequent increase in 2-AG. Thus, it is safe to assume that the entire system is actively involved in helping to combat nausea.
